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Rational Design of “Heat Seeking” Drug Loaded Polypeptide Nanoparticles That Thermally Target Solid Tumors

[Image: see text] This paper demonstrates the first example of targeting a solid tumor that is externally heated to 42 °C by “heat seeking” drug-loaded polypeptide nanoparticles. These nanoparticles consist of a thermally responsive elastin-like polypeptide (ELP) conjugated to multiple copies of a h...

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Detalles Bibliográficos
Autores principales:	McDaniel, Jonathan R., MacEwan, Sarah R., Li, Xinghai, Radford, D. Christopher, Landon, Chelsea D., Dewhirst, Mark, Chilkoti, Ashutosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025578/ https://www.ncbi.nlm.nih.gov/pubmed/24738626 http://dx.doi.org/10.1021/nl5009376

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