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Scalable Production of Highly Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor
[Image: see text] We have developed a novel, all-electronic biosensor for opioids that consists of an engineered μ-opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand binding. A variant of the receptor protein th...
Autores principales: | Lerner, Mitchell B., Matsunaga, Felipe, Han, Gang Hee, Hong, Sung Ju, Xi, Jin, Crook, Alexander, Perez-Aguilar, Jose Manuel, Park, Yung Woo, Saven, Jeffery G., Liu, Renyu, Johnson, A. T. Charlie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025580/ https://www.ncbi.nlm.nih.gov/pubmed/24742304 http://dx.doi.org/10.1021/nl5006349 |
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