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Parallel Solution-Phase Synthesis and General Biological Activity of a Uridine Antibiotic Analog Library

[Image: see text] A small library of ninety four uridine antibiotic analogs was synthesized, under the Pilot Scale Library (PSL) Program of the NIH Roadmap initiative, from amine 2 and carboxylic acids 33 and 77 in solution-phase fashion. Diverse aldehyde, sulfonyl chloride, and carboxylic acid reac...

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Detalles Bibliográficos
Autores principales: Moukha-chafiq, Omar, Reynolds, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025591/
https://www.ncbi.nlm.nih.gov/pubmed/24661222
http://dx.doi.org/10.1021/co4001452