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Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis

Autophagy is induced by many cytotoxic stimuli but it is often unclear whether, under specific conditions, autophagy plays a prosurvival or a prodeath role. To answer this critical question we developed a novel methodology that employs automated live microscopy and image analysis to measure autophag...

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Detalles Bibliográficos
Autores principales: Xu, Yangqing, Yuan, Junying, Lipinski, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026027/
https://www.ncbi.nlm.nih.gov/pubmed/23748697
http://dx.doi.org/10.4161/auto.25080