Cargando…
DNA Methylation in an Enhancer Region of the FADS Cluster Is Associated with FADS Activity in Human Liver
Levels of omega-6 (n-6) and omega-3 (n-3), long chain polyunsaturated fatty acids (LcPUFAs) such as arachidonic acid (AA; 20∶4, n-6), eicosapentaenoic acid (EPA; 20∶5, n-3) and docosahexaenoic acid (DHA; 22∶6, n-3) impact a wide range of biological activities, including immune signaling, inflammatio...
Autores principales: | Howard, Timothy D., Mathias, Rasika A., Seeds, Michael C., Herrington, David M., Hixson, James E., Shimmin, Lawrence C., Hawkins, Greg A., Sellers, Matthew, Ainsworth, Hannah C., Sergeant, Susan, Miller, Leslie R., Chilton, Floyd H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026313/ https://www.ncbi.nlm.nih.gov/pubmed/24842322 http://dx.doi.org/10.1371/journal.pone.0097510 |
Ejemplares similares
-
Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster
por: Rahbar, Elaheh, et al.
Publicado: (2017) -
Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression
por: Reynolds, Lindsay M., et al.
Publicado: (2018) -
Adaptive Evolution of the FADS Gene Cluster within Africa
por: Mathias, Rasika A., et al.
Publicado: (2012) -
FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids
por: Reynolds, Lindsay M., et al.
Publicado: (2020) -
Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer
por: Cui, Tao, et al.
Publicado: (2016)