Regulation of ABCC6 Trafficking and Stability by a Conserved C-terminal PDZ-Like Sequence

Mutations in the ABCC6 ABC-transporter are causative of pseudoxanthoma elasticum (PXE). The loss of functional ABCC6 protein in the basolateral membrane of the kidney and liver is putatively associated with altered secretion of a circulatory factor. As a result, systemic changes in elastic tissues a...

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Detalles Bibliográficos
Autores principales: Xue, Peng, Crum, Chelsea M., Thibodeau, Patrick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026322/
https://www.ncbi.nlm.nih.gov/pubmed/24840500
http://dx.doi.org/10.1371/journal.pone.0097360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026322/
https://www.ncbi.nlm.nih.gov/pubmed/24840500
http://dx.doi.org/10.1371/journal.pone.0097360

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