Cargando…

Inhibition of B7-1 (CD80) by RhuDex(®) reduces lipopolysaccharide-mediated inflammation in human atherosclerotic lesions

BACKGROUND: Atherosclerosis is based on a chronic inflammatory process including the innate and adaptive immune response. Costimulatory molecules and their receptors provide decisive signals for antigen-specific cell activation. The contribution of B7-related pathways to atherosclerosis has hardly b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doesch, Andreas O, Zhao, Li, Gleissner, Christian A, Akhavanpoor, Mohammadreza, Rohde, David, Okuyucu, Deniz, Hakimi, Maani, Dengler, Thomas J, Katus, Hugo A, Erbel, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026407/ https://www.ncbi.nlm.nih.gov/pubmed/24872677 http://dx.doi.org/10.2147/DDDT.S59594

Ejemplares similares

Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex®
por: Heninger, Anne-Kristin, et al.
Publicado: (2014)

CCL19 and CCL21 modulate the inflammatory milieu in atherosclerotic lesions
por: Akhavanpoor, Mohammadreza, et al.
Publicado: (2014)

Adventitial inflammation and its interaction with intimal atherosclerotic lesions
por: Akhavanpoor, Mohammadreza, et al.
Publicado: (2014)

Inflammatory therapeutic targets in coronary atherosclerosis—from molecular biology to clinical application
por: Linden, Fabian, et al.
Publicado: (2014)

CXCL4 Plasma Levels Are Not Associated with the Extent of Coronary Artery Disease or with Coronary Plaque Morphology
por: Erbel, Christian, et al.
Publicado: (2015)

Superior rejection profile during the first 24 months after heart transplantation under tacrolimus as baseline immunosuppressive regimen
por: Helmschrott, Matthias, et al.
Publicado: (2014)

Advantageous effects of immunosuppression with tacrolimus in comparison with cyclosporine A regarding renal function in patients after heart transplantation
por: Helmschrott, Matthias, et al.
Publicado: (2015)

PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels
por: Erbel, C, et al.
Publicado: (2011)

Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation
por: Domschke, Gabriele, et al.
Publicado: (2018)

Heart rate reduction for 36 months with ivabradine reduces left ventricular mass in cardiac allograft recipients: a long-term follow-up study
por: Doesch, Andreas O, et al.
Publicado: (2013)

Analysis of malignancies in patients after heart transplantation with subsequent immunosuppressive therapy
por: Rivinius, Rasmus, et al.
Publicado: (2014)

Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation
por: Rivinius, Rasmus, et al.
Publicado: (2016)

Effects of vildagliptin (Galvus®) therapy in patients with type 2 diabetes mellitus after heart transplantation
por: Gueler, Ibrahim, et al.
Publicado: (2013)

Identification of Specific Coronary Artery Disease Phenotypes Implicating Differential Pathophysiologies
por: Krohn, Jona B., et al.
Publicado: (2022)

Effects of oral valganciclovir prophylaxis for cytomegalovirus infection in heart transplant patients
por: Doesch, Andreas O, et al.
Publicado: (2012)

Conversion to generic cyclosporine A in stable chronic patients after heart transplantation
por: Kraeuter, Maximilian, et al.
Publicado: (2013)

The influence of surgical technique on early posttransplant atrial fibrillation – comparison of biatrial, bicaval, and total orthotopic heart transplantation
por: Rivinius, Rasmus, et al.
Publicado: (2017)

Increased adherence eight months after switch from twice daily calcineurin inhibitor based treatment to once daily modified released tacrolimus in heart transplantation
por: Doesch, Andreas O, et al.
Publicado: (2013)

Asialo-rhuEPO as a Potential Neuroprotectant for Ischemic Stroke Treatment
por: Kittur, Farooqahmed S., et al.
Publicado: (2023)

Constrictive Pericarditis in the Presence of Remaining Remnants of a Left Ventricular Assist Device in a Heart Transplanted Patient
por: Rivinius, R., et al.
Publicado: (2015)

Proinflammatory and prothrombotic effects on human vascular endothelial cells of Immune-cell-derived LIGHT
por: Celik, S, et al.
Publicado: (2009)

DEX, Delirium and Dilemma
por: Magoon, Rohan, et al.
Publicado: (2023)

r.hu-Erythropoietin (EPO) treatment of pre-ESRD patients slows the rate of progression of renal decline
por: Tapolyai, Mihály, et al.
Publicado: (2003)

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis
por: Rutgeerts, Paul J, et al.
Publicado: (2013)

Sargramostim (rhu GM-CSF) as Cancer Therapy (Systematic Review) and An Immunomodulator. A Drug Before Its Time?
por: Lazarus, Hillard M., et al.
Publicado: (2021)

Recombinant human plasma gelsolin (rhu-pGSN) in a patient hospitalized with critical COVID-19 pneumonia
por: Catteeuw, Julie V., et al.
Publicado: (2021)

Synergistic Effect of Perineural Dexamethasone and Dexmedetomidine (Dex-Dex) Prolong Analgesic Effect of a Preoperative Interscalene Block
por: Noor, Nazir A, et al.
Publicado: (2020)

Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor (rhu GM-CSF) as Adjuvant Therapy for Invasive Fungal Diseases
por: Chen, Tempe K, et al.
Publicado: (2022)

Synergistic Effect of Perineural Dexamethasone and Dexmedetomidine (Dex-Dex) in Extending the Analgesic Duration of Pectoral Type I and II Blocks
por: Zusman, Robert P, et al.
Publicado: (2020)

Correction: Synergistic Effect of Perineural Dexamethasone and Dexmedetomidine (Dex-Dex) Prolong Analgesic Effect of a Preoperative Interscalene Block
por: Noor, Nazir A, et al.
Publicado: (2020)

Phase I and Pharmacokinetic Study of HER2-targeted rhuMAb 2C4 (Pertuzumab, RO4368451) in Japanese Patients with Solid Tumors
por: Yamamoto, Noboru, et al.
Publicado: (2009)

Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases
por: Jankowsky, Eckhard, et al.
Publicado: (2006)

A procedure for Dex-induced gene transactivation in Arabidopsis ovules
por: Schubert, Jasmin, et al.
Publicado: (2022)

Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque
por: Carnevale, Roberto, et al.
Publicado: (2018)

DEAD/DExH-Box RNA Helicases in Selected Human Parasites
por: Marchat, Laurence A., et al.
Publicado: (2015)

BioCIDER: a Contextualisation InDEx for biological Resources discovery
por: Horro, Carlos, et al.
Publicado: (2017)

Coadministration of Stigmasterol and Dexamethasone (STIG+DEX) Modulates Steroid-Resistant Asthma
por: Hohoayi, Abigail, et al.
Publicado: (2022)

Dex-Benchmark: datasets and code to evaluate algorithms for transcriptomics data analysis
por: Xie, Zhuorui, et al.
Publicado: (2023)

Crystal structures of the DExH-box RNA helicase DHX9
por: Lee, Young-Tae, et al.
Publicado: (2023)

Cardiac magnetic resonance and computed tomography angiography for clinical imaging of stable coronary artery disease. Diagnostic classification and risk stratification
por: Korosoglou, Grigorios, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qk88bfqa11cih5pu1k8mqnv2c3