Dual inhibition of EGFR at protein and activity level via combinatorial blocking of PI4KIIα as anti-tumor strategy

Our previous studies indicate that phosphatidylinositol 4-kinase IIα can promote the growth of multi-malignant tumors via HER-2/PI3K and MAPK pathways. However, the molecular mechanisms of this pathway and its potential for clinical application remain unknown. In this study, we found that PI4KIIα co...

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Detalles Bibliográficos
Autores principales: Li, Jiangmei, Zhang, Lunfeng, Gao, Zhen, Kang, Hua, Rong, Guohua, Zhang, Xu, Chen, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026421/
https://www.ncbi.nlm.nih.gov/pubmed/24801752
http://dx.doi.org/10.1007/s13238-014-0055-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026421/
https://www.ncbi.nlm.nih.gov/pubmed/24801752
http://dx.doi.org/10.1007/s13238-014-0055-y

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