Mechanical Loading in Osteocytes Induces Formation of a Src/Pyk2/MBD2 Complex That Suppresses Anabolic Gene Expression

Mechanical stimulation of the skeleton promotes bone gain and suppresses bone loss, ultimately resulting in improved bone strength and fracture resistance. The molecular mechanisms directing anabolic and/or anti-catabolic actions on the skeleton during loading are not fully understood. Identifying m...

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Detalles Bibliográficos
Autores principales: Hum, Julia M., Day, Richard N., Bidwell, Joseph P., Wang, Yingxiao, Pavalko, Fredrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026426/
https://www.ncbi.nlm.nih.gov/pubmed/24841674
http://dx.doi.org/10.1371/journal.pone.0097942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026426/
https://www.ncbi.nlm.nih.gov/pubmed/24841674
http://dx.doi.org/10.1371/journal.pone.0097942

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