TLR4 Activation Promotes Podocyte Injury and Interstitial Fibrosis in Diabetic Nephropathy

Toll like receptor (TLR) 4 has been reported to promote inflammation in diabetic nephropathy. However the role of TLR4 in the complicated pathophysiology of diabetic nephropathy is not understood. In this study, we report elevated expression of TLR4, its endogenous ligands and downstream cytokines,...

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Detalles Bibliográficos
Autores principales: Ma, Jin, Chadban, Steven J., Zhao, Cathy Y., Chen, Xiaochen, Kwan, Tony, Panchapakesan, Usha, Pollock, Carol A., Wu, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026484/
https://www.ncbi.nlm.nih.gov/pubmed/24842252
http://dx.doi.org/10.1371/journal.pone.0097985

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