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Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity

Synthetic short interfering RNA (siRNA) oligonucleotides can trigger the RNA interference pathway and lead to selective gene silencing. Despite considerable enthusiasm and investment, formidable challenges remain that may deter translating this breakthrough discovery into clinical applications. In p...

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Detalles Bibliográficos
Autores principales:	Konca, Yeliz Utku, Kirshenbaum, Kent, Zuckermann, Ronald N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026564/ https://www.ncbi.nlm.nih.gov/pubmed/24872690 http://dx.doi.org/10.2147/IJN.S57449

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