Diversity and Bias through Receptor–Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization

Allosteric receptor–receptor interactions in GPCR heteromers appeared to introduce an intermolecular allosteric mechanism contributing to the diversity and bias in the protomers. Examples of dopamine D2R heteromerization are given to show how such allosteric mechanisms significantly change the recep...

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Detalles Bibliográficos
Autores principales: Fuxe, Kjell, Tarakanov, Alexander, Romero Fernandez, Wilber, Ferraro, Luca, Tanganelli, Sergio, Filip, Malgorzata, Agnati, Luigi F., Garriga, Pere, Diaz-Cabiale, Zaida, Borroto-Escuela, Dasiel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026686/
https://www.ncbi.nlm.nih.gov/pubmed/24860548
http://dx.doi.org/10.3389/fendo.2014.00071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026686/
https://www.ncbi.nlm.nih.gov/pubmed/24860548
http://dx.doi.org/10.3389/fendo.2014.00071

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