Cargando…
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
Mutations in hemojuvelin (HJV) are the most common cause of the juvenile-onset form of the iron overload disorder hereditary hemochromatosis. The discovery that HJV functions as a co-receptor for the bone morphogenetic protein (BMP) family of signaling molecules helped to identify this signaling pat...
Autores principales: | Core, Amanda B., Canali, Susanna, Babitt, Jodie L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026703/ https://www.ncbi.nlm.nih.gov/pubmed/24860505 http://dx.doi.org/10.3389/fphar.2014.00104 |
Ejemplares similares
-
BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin
por: Gibert, Yann, et al.
Publicado: (2011) -
Vitamin A deficiency modulates iron metabolism independent of hemojuvelin (Hfe2) and bone morphogenetic protein 6 (Bmp6) transcript levels
por: Mendes, Juliana Frossard Ribeiro, et al.
Publicado: (2016) -
Effect of Iron Overload and Iron Deficiency on Liver Hemojuvelin Protein
por: Krijt, Jan, et al.
Publicado: (2012) -
Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs)
por: Wu, Qifang, et al.
Publicado: (2012) -
A Process for the Design and Development of Novel Bone Morphogenetic Protein-7 (BMP-7) Mimetics With an Example: THR-184
por: Carlson, William D., et al.
Publicado: (2022)