KRAS Mutation Detection in Non-small Cell Lung Cancer Using a Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping Method and Comparative Validation with Next-Generation Sequencing

BACKGROUND: KRAS is one of commonly mutated genetic "drivers" in non-small cell lung cancers (NSCLCs). Recent studies indicate that patients with KRAS-mutated tumors do not benefit from adjuvant chemotherapy, so there is now a focus on targeting KRAS-mutated NSCLCs. A feasible mutation det...

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Detalles Bibliográficos
Autores principales: Lee, Boram, Lee, Boin, Han, Gangmin, Kwon, Mi Jung, Han, Joungho, Choi, Yoon-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026800/
https://www.ncbi.nlm.nih.gov/pubmed/24868222
http://dx.doi.org/10.4132/KoreanJPathol.2014.48.2.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026800/
https://www.ncbi.nlm.nih.gov/pubmed/24868222
http://dx.doi.org/10.4132/KoreanJPathol.2014.48.2.100

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