Interaction Study of an Amorphous Solid Dispersion of Cyclosporin A in Poly-Alpha-Cyclodextrin with Model Membranes by (1)H-, (2)H-, (31)P-NMR and Electron Spin Resonance

The properties of an amorphous solid dispersion of cyclosporine A (ASD) prepared with the copolymer alpha cyclodextrin (POLYA) and cyclosporine A (CYSP) were investigated by (1)H-NMR in solution and its membrane interactions were studied by (1)H-NMR in small unilamellar vesicles and by (31)P (2)H NM...

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Detalles Bibliográficos
Autores principales: Debouzy, Jean-Claude, Crouzier, David, Bourbon, Fréderic, Lahiani-Skiba, Malika, Skiba, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027026/
https://www.ncbi.nlm.nih.gov/pubmed/24883210
http://dx.doi.org/10.1155/2014/575719

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