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Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010

PURPOSE: Previous reports show an association between high serum ferritin levels and metabolic syndrome (MS) in adults. In adolescents, little information is available with obesity and serum ferritin levels. METHODS: This is a cross-sectional study. Data were obtained from the 5th Korean National He...

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Autores principales: Jeon, Yeon Jin, Jung, In Ah, Kim, Shin Hee, Cho, Won-Kyoung, Jeong, Seung Hee, Cho, Kyoung Soon, Park, So Hyun, Jung, Min Ho, Suh, Byung-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pediatric Endocrinology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027078/
https://www.ncbi.nlm.nih.gov/pubmed/24904868
http://dx.doi.org/10.6065/apem.2013.18.3.141
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author Jeon, Yeon Jin
Jung, In Ah
Kim, Shin Hee
Cho, Won-Kyoung
Jeong, Seung Hee
Cho, Kyoung Soon
Park, So Hyun
Jung, Min Ho
Suh, Byung-Kyu
author_facet Jeon, Yeon Jin
Jung, In Ah
Kim, Shin Hee
Cho, Won-Kyoung
Jeong, Seung Hee
Cho, Kyoung Soon
Park, So Hyun
Jung, Min Ho
Suh, Byung-Kyu
author_sort Jeon, Yeon Jin
collection PubMed
description PURPOSE: Previous reports show an association between high serum ferritin levels and metabolic syndrome (MS) in adults. In adolescents, little information is available with obesity and serum ferritin levels. METHODS: This is a cross-sectional study. Data were obtained from the 5th Korean National Health and Nutrition Examination Survey (K-NHANES) conducted during 2010 by the Korean Ministry of Health and Welfare. A total of 849 subjects aged 10-18 years participated in the 2010 survey. A body mass index (BMI) ≥95th percentile for age and sex or a BMI ≥25 was used to diagnose as obesity. RESULTS: The weighted prevalence of obesity was 13.4% (62/462) in male and 8.5% (33/387) in female. We observed significantly higher serum ferritin in male than in female (mean±standard error [SE], 50.5±2.3 µU/L vs. 30.6±1.3 µU/L; P<0.0001). In male, serum ferritin is positively correlated with age (P<0.0001). White blood cell (WBC) count, serum fasting blood sugar, triglyceride (TG), total cholesterol, low-density lipoprotein, insulin, homeostasis model assessment-insulin resistance (HOMA-IR), systolic and diastolic blood pressure, and ferritin levels were higher and high-density lipoprotein (HDL) were lower in the obesity than in the normal group. In female adolescents, WBC count, TG, insulin, and HOMA-IR were higher and HDL were lower in the obesity than in the normal group. In male, serum ferritin levels showed positive association with obesity (β=21.196, P=0.016). CONCLUSION: Serum ferritin levels appear to be associated with obesity in Korean male adolescents.
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spelling pubmed-40270782014-06-05 Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010 Jeon, Yeon Jin Jung, In Ah Kim, Shin Hee Cho, Won-Kyoung Jeong, Seung Hee Cho, Kyoung Soon Park, So Hyun Jung, Min Ho Suh, Byung-Kyu Ann Pediatr Endocrinol Metab Original Article PURPOSE: Previous reports show an association between high serum ferritin levels and metabolic syndrome (MS) in adults. In adolescents, little information is available with obesity and serum ferritin levels. METHODS: This is a cross-sectional study. Data were obtained from the 5th Korean National Health and Nutrition Examination Survey (K-NHANES) conducted during 2010 by the Korean Ministry of Health and Welfare. A total of 849 subjects aged 10-18 years participated in the 2010 survey. A body mass index (BMI) ≥95th percentile for age and sex or a BMI ≥25 was used to diagnose as obesity. RESULTS: The weighted prevalence of obesity was 13.4% (62/462) in male and 8.5% (33/387) in female. We observed significantly higher serum ferritin in male than in female (mean±standard error [SE], 50.5±2.3 µU/L vs. 30.6±1.3 µU/L; P<0.0001). In male, serum ferritin is positively correlated with age (P<0.0001). White blood cell (WBC) count, serum fasting blood sugar, triglyceride (TG), total cholesterol, low-density lipoprotein, insulin, homeostasis model assessment-insulin resistance (HOMA-IR), systolic and diastolic blood pressure, and ferritin levels were higher and high-density lipoprotein (HDL) were lower in the obesity than in the normal group. In female adolescents, WBC count, TG, insulin, and HOMA-IR were higher and HDL were lower in the obesity than in the normal group. In male, serum ferritin levels showed positive association with obesity (β=21.196, P=0.016). CONCLUSION: Serum ferritin levels appear to be associated with obesity in Korean male adolescents. The Korean Society of Pediatric Endocrinology 2013-09 2013-09-30 /pmc/articles/PMC4027078/ /pubmed/24904868 http://dx.doi.org/10.6065/apem.2013.18.3.141 Text en © 2013 Annals of Pediatric Endocrinology & Metabolism http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jeon, Yeon Jin
Jung, In Ah
Kim, Shin Hee
Cho, Won-Kyoung
Jeong, Seung Hee
Cho, Kyoung Soon
Park, So Hyun
Jung, Min Ho
Suh, Byung-Kyu
Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010
title Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010
title_full Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010
title_fullStr Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010
title_full_unstemmed Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010
title_short Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010
title_sort serum ferritin level is higher in male adolescents with obesity: results from the korean national health and nutrition examination survey 2010
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027078/
https://www.ncbi.nlm.nih.gov/pubmed/24904868
http://dx.doi.org/10.6065/apem.2013.18.3.141
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