Crystal structure of the 5hmC specific endonuclease PvuRts1I

PvuRts1I is a prototype for a larger family of restriction endonucleases that cleave DNA containing 5-hydroxymethylcytosine (5hmC) or 5-glucosylhydroxymethylcytosine (5ghmC), but not 5-methylcytosine (5mC) or cytosine. Here, we report a crystal structure of the enzyme at 2.35 Å resolution. Although...

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Detalles Bibliográficos
Autores principales: Kazrani, Asgar Abbas, Kowalska, Monika, Czapinska, Honorata, Bochtler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027163/
https://www.ncbi.nlm.nih.gov/pubmed/24634440
http://dx.doi.org/10.1093/nar/gku186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027163/
https://www.ncbi.nlm.nih.gov/pubmed/24634440
http://dx.doi.org/10.1093/nar/gku186

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