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Crystal structure of the 5hmC specific endonuclease PvuRts1I
PvuRts1I is a prototype for a larger family of restriction endonucleases that cleave DNA containing 5-hydroxymethylcytosine (5hmC) or 5-glucosylhydroxymethylcytosine (5ghmC), but not 5-methylcytosine (5mC) or cytosine. Here, we report a crystal structure of the enzyme at 2.35 Å resolution. Although...
Autores principales: | Kazrani, Asgar Abbas, Kowalska, Monika, Czapinska, Honorata, Bochtler, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027163/ https://www.ncbi.nlm.nih.gov/pubmed/24634440 http://dx.doi.org/10.1093/nar/gku186 |
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