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Impact of sequencing depth in ChIP-seq experiments

In a chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) experiment, an important consideration in experimental design is the minimum number of sequenced reads required to obtain statistically significant results. We present an extensive evaluation of the impact of sequen...

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Detalles Bibliográficos
Autores principales: Jung, Youngsook L., Luquette, Lovelace J., Ho, Joshua W.K., Ferrari, Francesco, Tolstorukov, Michael, Minoda, Aki, Issner, Robbyn, Epstein, Charles B., Karpen, Gary H., Kuroda, Mitzi I., Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027199/
https://www.ncbi.nlm.nih.gov/pubmed/24598259
http://dx.doi.org/10.1093/nar/gku178

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