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Systematic design and functional analysis of artificial microRNAs

Unlike short interfering RNAs (siRNAs), which are commonly designed to repress a single messenger RNA (mRNA) target through perfect base pairing, microRNAs (miRNAs) are endogenous small RNAs that have evolved to concurrently repress multiple mRNA targets through imperfect complementarity. MicroRNA t...

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Detalles Bibliográficos
Autores principales:	Arroyo, Jason D., Gallichotte, Emily N., Tewari, Muneesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027203/ https://www.ncbi.nlm.nih.gov/pubmed/24598260 http://dx.doi.org/10.1093/nar/gku171

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