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The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor
Post-translational modifications (such as ubiquitination) of clock proteins are critical in maintaining the precision and robustness of the evolutionarily conserved circadian clock. Ubiquitination of the core clock transcription factor BMAL1 (brain and muscle Arnt-like 1) has recently been reported....
Autores principales: | Gossan, Nicole C., Zhang, Feng, Guo, Baoqiang, Jin, Ding, Yoshitane, Hikari, Yao, Aiyu, Glossop, Nick, Zhang, Yong Q., Fukada, Yoshitaka, Meng, Qing-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027211/ https://www.ncbi.nlm.nih.gov/pubmed/24728990 http://dx.doi.org/10.1093/nar/gku225 |
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