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Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver
Development of a safe and effective method for gene delivery to hepatocytes is a critical step toward gene therapy for liver diseases. Here, we assessed the parameters for gene delivery to the livers of large animals (pigs, 40–65 kg) using an image-guided hydrodynamics-based procedure that involves...
Autores principales: | Kamimura, Kenya, Suda, Takeshi, Zhang, Guisheng, Aoyagi, Yutaka, Liu, Dexi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027427/ https://www.ncbi.nlm.nih.gov/pubmed/24129227 http://dx.doi.org/10.1038/mtna.2013.52 |
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