Action Tremor Associated with Lamotrigine Monotherapy

Lamotrigine (LTG) is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use. Based on the temporal relationship, it is conceivable...

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Detalles Bibliográficos
Autores principales: Yang, Ji-Hye, Chung, Sung-Woo, Kim, Joong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Movement Disorder Society 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027652/
https://www.ncbi.nlm.nih.gov/pubmed/24868374
http://dx.doi.org/10.14802/jmd.10005
Descripción
Sumario:Lamotrigine (LTG) is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use. Based on the temporal relationship, it is conceivable that lamotrigine increases serotonin transmission or affects basal ganglia dopamine activity, thereby causing the tremor.

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