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Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China

BACKGROUND AND PURPOSE: Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population. METHODS: A Botulinu...

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Detalles Bibliográficos
Autores principales: Wang, Li, Hu, Xingyue, Liu, Chunfeng, Wu, Yiwen, Wang, Changqing, Wang, Zhiqiang, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Movement Disorder Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027674/
https://www.ncbi.nlm.nih.gov/pubmed/24868406
http://dx.doi.org/10.14802/jmd.12003
Descripción
Sumario:BACKGROUND AND PURPOSE: Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population. METHODS: A Botulinum Toxin Clinic-based study was conducted in the period 18 May through 8 October 2010 in East China. We identified 523 dystonia patients from the Movement disorders and Botulinum Toxin clinic Cases. RESULTS: The most common focal dystonia were blepharospasm (59%), cervical dystonia (35%), limb dystonia (3%), oromandibular dystonia (2%) and laryngeal dystonia (1%). Males with primary dystonia were noted to have earlier age of onset. A female predominance was noted for most of the primary dystonias with a male to female ratio (M : F) ranging from 1 : 1.48 to 1 : 3. CONCLUSIONS: The epidemiological features of dystonia in East China we collected were similar to the report in Japan which contrasts partly with that reported in Europe.