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Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China
BACKGROUND AND PURPOSE: Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population. METHODS: A Botulinu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Movement Disorder Society
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027674/ https://www.ncbi.nlm.nih.gov/pubmed/24868406 http://dx.doi.org/10.14802/jmd.12003 |
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author | Wang, Li Hu, Xingyue Liu, Chunfeng Wu, Yiwen Wang, Changqing Wang, Zhiqiang Chen, Jun |
author_facet | Wang, Li Hu, Xingyue Liu, Chunfeng Wu, Yiwen Wang, Changqing Wang, Zhiqiang Chen, Jun |
author_sort | Wang, Li |
collection | PubMed |
description | BACKGROUND AND PURPOSE: Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population. METHODS: A Botulinum Toxin Clinic-based study was conducted in the period 18 May through 8 October 2010 in East China. We identified 523 dystonia patients from the Movement disorders and Botulinum Toxin clinic Cases. RESULTS: The most common focal dystonia were blepharospasm (59%), cervical dystonia (35%), limb dystonia (3%), oromandibular dystonia (2%) and laryngeal dystonia (1%). Males with primary dystonia were noted to have earlier age of onset. A female predominance was noted for most of the primary dystonias with a male to female ratio (M : F) ranging from 1 : 1.48 to 1 : 3. CONCLUSIONS: The epidemiological features of dystonia in East China we collected were similar to the report in Japan which contrasts partly with that reported in Europe. |
format | Online Article Text |
id | pubmed-4027674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Movement Disorder Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-40276742014-05-27 Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China Wang, Li Hu, Xingyue Liu, Chunfeng Wu, Yiwen Wang, Changqing Wang, Zhiqiang Chen, Jun J Mov Disord Original Article BACKGROUND AND PURPOSE: Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population. METHODS: A Botulinum Toxin Clinic-based study was conducted in the period 18 May through 8 October 2010 in East China. We identified 523 dystonia patients from the Movement disorders and Botulinum Toxin clinic Cases. RESULTS: The most common focal dystonia were blepharospasm (59%), cervical dystonia (35%), limb dystonia (3%), oromandibular dystonia (2%) and laryngeal dystonia (1%). Males with primary dystonia were noted to have earlier age of onset. A female predominance was noted for most of the primary dystonias with a male to female ratio (M : F) ranging from 1 : 1.48 to 1 : 3. CONCLUSIONS: The epidemiological features of dystonia in East China we collected were similar to the report in Japan which contrasts partly with that reported in Europe. The Korean Movement Disorder Society 2012-05-30 2012-05 /pmc/articles/PMC4027674/ /pubmed/24868406 http://dx.doi.org/10.14802/jmd.12003 Text en Copyright © 2012 The Korean Movement Disorder Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Wang, Li Hu, Xingyue Liu, Chunfeng Wu, Yiwen Wang, Changqing Wang, Zhiqiang Chen, Jun Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China |
title | Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China |
title_full | Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China |
title_fullStr | Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China |
title_full_unstemmed | Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China |
title_short | Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China |
title_sort | botulinum toxin clinic-based epidemiologic survey of adults with primary dystonia in east china |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027674/ https://www.ncbi.nlm.nih.gov/pubmed/24868406 http://dx.doi.org/10.14802/jmd.12003 |
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