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The dark side of DNA repair

The BER pathway is widely used to repair DNA damage in cells, but it can also introduce unwanted mutations and is sometimes hijacked by other pathways.

Detalles Bibliográficos
Autor principal: Wilson, Samuel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027859/
https://www.ncbi.nlm.nih.gov/pubmed/24844708
http://dx.doi.org/10.7554/eLife.03068
Descripción
Sumario:The BER pathway is widely used to repair DNA damage in cells, but it can also introduce unwanted mutations and is sometimes hijacked by other pathways.