Cargando…

NMR-Based Approaches for the Identification and Optimization of Inhibitors of Protein–Protein Interactions

Detalles Bibliográficos
Autores principales:	Barile, Elisa, Pellecchia, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027952/ https://www.ncbi.nlm.nih.gov/pubmed/24712885 http://dx.doi.org/10.1021/cr500043b

Ejemplares similares

Mixture-Based Screening of Focused Combinatorial Libraries by NMR: Application to the Antiapoptotic Protein hMcl-1
por: Alboreggia, Giulia, et al.
Publicado: (2023)

Competition NMR for Detection of Hit/Lead Inhibitors of Protein–Protein Interactions
por: Musielak, Bogdan, et al.
Publicado: (2020)

Identification of interaction partners using protein aggregation and NMR spectroscopy
por: Chae, Young Kee, et al.
Publicado: (2022)

Exploring NMR ensembles of calcium binding proteins: Perspectives to design inhibitors of protein-protein interactions
por: Isvoran, Adriana, et al.
Publicado: (2011)

(S)Pinning down protein interactions by NMR
por: Teilum, Kaare, et al.
Publicado: (2017)

NMR Characterization of the Interactions Between Glycosaminoglycans and Proteins
por: Bu, Changkai, et al.
Publicado: (2021)

Exploring multivalent carbohydrate–protein interactions by NMR
por: Quintana, Jon I., et al.
Publicado: (2023)

PI by NMR: Probing CH–π Interactions in Protein–Ligand Complexes by NMR Spectroscopy
por: Platzer, Gerald, et al.
Publicado: (2020)

Optimization of protein samples for NMR using thermal shift assays
por: Kozak, Sandra, et al.
Publicado: (2016)

Molecular Dynamics-Assisted Optimization of Protein NMR Relaxation Analysis
por: Anderson, Janet S., et al.
Publicado: (2022)

The Use of NMR to Study Transient Carbohydrate—Protein Interactions
por: Nieto, Pedro M.
Publicado: (2018)

Glycan structures and their interactions with proteins. A NMR view
por: Gimeno, Ana, et al.
Publicado: (2020)

NMR Lineshape Analysis of Intrinsically Disordered Protein Interactions
por: Waudby, Christopher A., et al.
Publicado: (2020)

An Optically Pure Apogossypolone Derivative as Potent Pan-Active Inhibitor of Anti-Apoptotic Bcl-2 Family Proteins
por: Wei, Jun, et al.
Publicado: (2011)

Investigating the Dynamic Aspects of Drug-Protein Recognition through a Combination of MD and NMR Analyses: Implications for the Development of Protein-Protein Interaction Inhibitors
por: Meli, Massimiliano, et al.
Publicado: (2014)

Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein–Protein Interactions?
por: Dias, David M., et al.
Publicado: (2013)

Identification of hot regions in hub protein–protein interactions by clustering and PPRA optimization
por: Lin, Xiaoli, et al.
Publicado: (2021)

Detergent Optimized Membrane Protein Reconstitution in Liposomes for Solid State NMR
por: Murray, Dylan T., et al.
Publicado: (2014)

Site-Resolved Measurement of Water-Protein Interactions by Solution NMR
por: Nucci, Nathaniel V., et al.
Publicado: (2011)

Intermolecular Interactions and Protein Dynamics by Solid‐State NMR Spectroscopy
por: Lamley, Jonathan M., et al.
Publicado: (2015)

Intermolecular Interactions and Protein Dynamics by Solid‐State NMR Spectroscopy
por: Lamley, Jonathan M., et al.
Publicado: (2015)

Glycosaminoglycan-Protein Interactions by Nuclear Magnetic Resonance (NMR) Spectroscopy
por: Pomin, Vitor H., et al.
Publicado: (2018)

In-Cell NMR: Analysis of Protein–Small Molecule Interactions, Metabolic Processes, and Protein Phosphorylation
por: Kumar, Amit, et al.
Publicado: (2019)

Active metabolism unmasks functional protein–protein interactions in real time in-cell NMR
por: Breindel, Leonard, et al.
Publicado: (2020)

Imbalance in chemical space: How to facilitate the identification of protein-protein interaction inhibitors
por: Kuenemann, Mélaine A., et al.
Publicado: (2016)

Identification of small-molecule protein–protein interaction inhibitors for NKG2D
por: Thompson, Aaron A., et al.
Publicado: (2023)

Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors
por: El Hage, Krystel, et al.
Publicado: (2023)

Peptide‐based covalent inhibitors of protein–protein interactions
por: Paulussen, Felix M., et al.
Publicado: (2022)

In silico Approaches for the Design and Optimization of Interfering Peptides Against Protein–Protein Interactions
por: Hashemi, Zahra Sadat, et al.
Publicado: (2021)

Optimization and validation of multi-state NMR protein structures using structural correlations
por: Ashkinadze, Dzmitry, et al.
Publicado: (2022)

GeNMR: a web server for rapid NMR-based protein structure determination
por: Berjanskii, Mark, et al.
Publicado: (2009)

Identification of Inhibitors of Biological Interactions Involving Intrinsically Disordered Proteins
por: Marasco, Daniela, et al.
Publicado: (2015)

Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS)
por: Hetherington, Kristina, et al.
Publicado: (2021)

(13)C NMR Reveals No Evidence of n−π* Interactions in Proteins
por: Worley, Bradley, et al.
Publicado: (2012)

Protein interaction patterns in different cellular environments are revealed by in-cell NMR
por: Barbieri, Letizia, et al.
Publicado: (2015)

Interaction of Hyaluronan Acid with Some Proteins in Aqueous Solution as Studied by NMR
por: Melnikova, Daria, et al.
Publicado: (2023)

Time-optimized protein NMR assignment with an integrative deep learning approach using AlphaFold and chemical shift prediction
por: Klukowski, Piotr, et al.
Publicado: (2023)

Fundamentals of Protein NMR Spectroscopy
por: Rule, Gordon S, et al.
Publicado: (2006)

Computer- and NMR-Aided Design of Small-Molecule Inhibitors of the Hub1 Protein
por: Reyes Romero, Atilio, et al.
Publicado: (2022)

Ψ-Footprinting approach for the identification of protein synthesis inhibitor producers
por: Handel, Franziska, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dbkdkj4pv94k38t9ifrmik03pc