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R88-APOBEC3Gm Inhibits the Replication of Both Drug-resistant Strains of HIV-1 and Viruses Produced From Latently Infected Cells

Human immunodeficiency virus type 1 (HIV-1) drug resistance and the latent reservoir are the two major obstacles to effectively controlling and curing HIV-1 infection. Therefore, it is critical to develop therapeutic strategies specifically targeting these two obstacles. Recently, we described a nov...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxia, Ao, Zhujun, Danappa Jayappa, Kallesh, Shi, Bei, Kobinger, Gary, Yao, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027983/
https://www.ncbi.nlm.nih.gov/pubmed/24594845
http://dx.doi.org/10.1038/mtna.2014.2