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Congenic Mapping and Allele-Specific Alteration Analysis of Stmm1 Locus Conferring Resistance to Early-Stage Chemically Induced Skin Papillomas
Genome-wide association studies have revealed that many low-penetrance cancer susceptibility loci are located throughout the genome; however, a very limited number of genes have been identified so far. Using a forward genetics approach to map such loci in a mouse skin cancer model, we previously ide...
Autores principales: | Okumura, Kazuhiro, Saito, Megumi, Isogai, Eriko, Miura, Ikuo, Wakana, Shigeharu, Kominami, Ryo, Wakabayashi, Yuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028187/ https://www.ncbi.nlm.nih.gov/pubmed/24844776 http://dx.doi.org/10.1371/journal.pone.0097201 |
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