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Serum Amyloid A Induces NLRP-3-Mediated IL-1β Secretion in Neutrophils
BACKGROUND/AIMS: Serum amyloid A (SAA) is an acute phase reactant with significant immunological activities, including effects on cytokine synthesis and neutrophil chemotaxis. Neutrophils can also release cytokines with proinflammatory properties. IL-1β is a key proinflammatory cytokine, the secreti...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028190/ https://www.ncbi.nlm.nih.gov/pubmed/24846290 http://dx.doi.org/10.1371/journal.pone.0096703 |