Delayed Administration of a Bio-Engineered Zinc-Finger VEGF-A Gene Therapy Is Neuroprotective and Attenuates Allodynia Following Traumatic Spinal Cord Injury

Following spinal cord injury (SCI) there are drastic changes that occur in the spinal microvasculature, including ischemia, hemorrhage, endothelial cell death and blood-spinal cord barrier disruption. Vascular endothelial growth factor-A (VEGF-A) is a pleiotropic factor recognized for its pro-angiog...

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Detalles Bibliográficos
Autores principales: Figley, Sarah A., Liu, Yang, Karadimas, Spyridon K., Satkunendrarajah, Kajana, Fettes, Peter, Spratt, S. Kaye, Lee, Gary, Ando, Dale, Surosky, Richard, Giedlin, Martin, Fehlings, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028194/
https://www.ncbi.nlm.nih.gov/pubmed/24846143
http://dx.doi.org/10.1371/journal.pone.0096137

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