Anti-Cancer Potential of MAPK Pathway Inhibition in Paragangliomas–Effect of Different Statins on Mouse Pheochromocytoma Cells

To date, malignant pheochromocytomas and paragangliomas (PHEOs/PGLs) cannot be effectively cured and thus novel treatment strategies are urgently needed. Lovastatin has been shown to effectively induce apoptosis in mouse PHEO cells (MPC) and the more aggressive mouse tumor tissue-derived cells (MTT)...

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Detalles Bibliográficos
Autores principales: Fliedner, Stephanie M. J., Engel, Tobias, Lendvai, Nikoletta K., Shankavaram, Uma, Nölting, Svenja, Wesley, Robert, Elkahloun, Abdel G., Ungefroren, Hendrik, Oldoerp, Angela, Lampert, Gary, Lehnert, Hendrik, Timmers, Henri, Pacak, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028222/
https://www.ncbi.nlm.nih.gov/pubmed/24846270
http://dx.doi.org/10.1371/journal.pone.0097712

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