Allogeneic Splenocyte Transfer and Lipopolysaccharide Inhalations Induce Differential T Cell Expansion and Lung Injury: A Novel Model of Pulmonary Graft-versus-Host Disease

BACKGROUND: Pulmonary GVHD (pGVHD) is an important complication of hematopoietic cell transplant (HCT) and is thought to be a consequence of the HCT conditioning regimen, allogeneic donor cells, and posttransplant lung exposures. We have previously demonstrated that serial inhaled lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Martinu, Tereza, Kinnier, Christine V., Sun, Jesse, Kelly, Francine L., Nelson, Margaret E., Garantziotis, Stavros, Foster, W. Michael, Palmer, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028236/
https://www.ncbi.nlm.nih.gov/pubmed/24844383
http://dx.doi.org/10.1371/journal.pone.0097951

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