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Avidity-Dependent Programming of Autoreactive T Cells in T1D

Fate determination for autoreactive T cells relies on a series of avidity-dependent interactions during T cell selection, represented by two general types of signals, one based on antigen expression and density during T cell development, and one based on genes that interpret the avidity of TCR inter...

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Detalles Bibliográficos
Autores principales: Durinovic-Belló, Ivana, Gersuk, Vivian H., Ni, Chester, Wu, Rebecca, Thorpe, Jerill, Jospe, Nicholas, Sanda, Srinath, Greenbaum, Carla J., Nepom, Gerald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028311/
https://www.ncbi.nlm.nih.gov/pubmed/24844227
http://dx.doi.org/10.1371/journal.pone.0098074