MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age

To study mitochondrial protein age dynamics, we targeted a time-sensitive fluorescent protein, MitoTimer, to the mitochondrial matrix. Mitochondrial age was revealed by the integrated portions of young (green) and old (red) MitoTimer protein. Mitochondrial protein age was dependent on turnover rates...

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Detalles Bibliográficos
Autores principales: Ferree, Andrew W, Trudeau, Kyle, Zik, Eden, Benador, Ilan Y, Twig, Gilad, Gottlieb, Roberta A, Shirihai, Orian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028338/
https://www.ncbi.nlm.nih.gov/pubmed/24149000
http://dx.doi.org/10.4161/auto.26503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028338/
https://www.ncbi.nlm.nih.gov/pubmed/24149000
http://dx.doi.org/10.4161/auto.26503

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