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Repeated TALEs: Visualizing DNA sequence localization and chromosome dynamics in live cells

Three recent papers, published just weeks apart, describe the use of fluorescent TALEs to tag specific DNA sequences in live cells and, in one case, also in fixed cells, the latter with potential clinical applications.

Detalles Bibliográficos
Autor principal: Pederson, Thoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028351/
https://www.ncbi.nlm.nih.gov/pubmed/24637394
http://dx.doi.org/10.4161/nucl.28143
Descripción
Sumario:Three recent papers, published just weeks apart, describe the use of fluorescent TALEs to tag specific DNA sequences in live cells and, in one case, also in fixed cells, the latter with potential clinical applications.