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Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study

PURPOSE: Ulinastatin, a serine protease inhibitor, inhibits several pro-inflammatory proteases and decreases inflammatory cytokine levels and mortality in experimental sepsis. We studied the effect of ulinastatin on 28-day all-cause mortality in a double-blind trial in patients with severe sepsis in...

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Detalles Bibliográficos
Autores principales:	Karnad, Dilip R., Bhadade, Rakesh, Verma, Pradeep K., Moulick, Nivedita D., Daga, Mradul K., Chafekar, Neelima D., Iyer, Shivakumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Original
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028549/ https://www.ncbi.nlm.nih.gov/pubmed/24737258 http://dx.doi.org/10.1007/s00134-014-3278-8

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