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Architectural and thermodynamic principles underlying intramembrane protease function
Intramembrane proteases hydrolyze peptide bonds within the membrane as a signaling paradigm universal to all life forms and with implications in disease. Deciphering the architectural strategies supporting intramembrane proteolysis is an essential but unattained goal. We integrated a new, quantitati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028635/ https://www.ncbi.nlm.nih.gov/pubmed/22797666 http://dx.doi.org/10.1038/nchembio.1021 |