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Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid

BACKGROUND: The roles of caspase 3 on the kainic acid-mediated neurodegeneration, dendritic plasticity alteration, neurogenesis, microglial activation and gliosis are not fully understood. Here, we investigate hippocampal changes using a mouse model that receive a single kainic acid-intracerebral ve...

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Detalles Bibliográficos
Autores principales: Tzeng, Tsai-Teng, Tsay, Huey-Jen, Chang, Luping, Hsu, Chia-Lin, Lai, Tzu-Hsuan, Huang, Fong-Lee, Shiao, Young-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028745/
https://www.ncbi.nlm.nih.gov/pubmed/24313976
http://dx.doi.org/10.1186/1423-0127-20-90