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A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature

BACKGROUND: The working environment of stone miners has been believed to cause their susceptibility to respiratory diseases. Silicosis is an occupational disease caused by exposure to crystalline silica dust which is marked by inflammation and scarring in the lung. The immune system boosted after th...

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Autores principales: Jiang, Yajian, Shao, Fangchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028864/
https://www.ncbi.nlm.nih.gov/pubmed/24314106
http://dx.doi.org/10.1186/1471-2466-13-71
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author Jiang, Yajian
Shao, Fangchun
author_facet Jiang, Yajian
Shao, Fangchun
author_sort Jiang, Yajian
collection PubMed
description BACKGROUND: The working environment of stone miners has been believed to cause their susceptibility to respiratory diseases. Silicosis is an occupational disease caused by exposure to crystalline silica dust which is marked by inflammation and scarring in the lung. The immune system boosted after the silica invasion led to self-damage and lay the foundation of silicosis pathogenesis. Silicosis coexisting with other diseases in one patient has been reported, however, was not reported to coexist with constrictive pericarditis. We, for the first time, reported a patient with silicosis and constrictive pericarditis and thought the immune response was probably the link between the two. CASE PRESENTATION: A 59-year-old Chinese stone miner complained of chest distress was found to have lung nodules which were found to be silica deposits by biopsy. This patient was also found to have constrictive pericarditis at the same time. Later surgical decortication cured his symptoms. CONCLUSION: We provided the first case having constrictive pericarditis concomitant with silicosis. A probable link between the two diseases was the immune response boosted by the silica deposits.
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spelling pubmed-40288642014-05-22 A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature Jiang, Yajian Shao, Fangchun BMC Pulm Med Case Report BACKGROUND: The working environment of stone miners has been believed to cause their susceptibility to respiratory diseases. Silicosis is an occupational disease caused by exposure to crystalline silica dust which is marked by inflammation and scarring in the lung. The immune system boosted after the silica invasion led to self-damage and lay the foundation of silicosis pathogenesis. Silicosis coexisting with other diseases in one patient has been reported, however, was not reported to coexist with constrictive pericarditis. We, for the first time, reported a patient with silicosis and constrictive pericarditis and thought the immune response was probably the link between the two. CASE PRESENTATION: A 59-year-old Chinese stone miner complained of chest distress was found to have lung nodules which were found to be silica deposits by biopsy. This patient was also found to have constrictive pericarditis at the same time. Later surgical decortication cured his symptoms. CONCLUSION: We provided the first case having constrictive pericarditis concomitant with silicosis. A probable link between the two diseases was the immune response boosted by the silica deposits. BioMed Central 2013-12-06 /pmc/articles/PMC4028864/ /pubmed/24314106 http://dx.doi.org/10.1186/1471-2466-13-71 Text en Copyright © 2013 Jiang and Shao; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jiang, Yajian
Shao, Fangchun
A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
title A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
title_full A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
title_fullStr A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
title_full_unstemmed A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
title_short A stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
title_sort stone miner with both silicosis and constrictive pericarditis: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028864/
https://www.ncbi.nlm.nih.gov/pubmed/24314106
http://dx.doi.org/10.1186/1471-2466-13-71
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