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Cholesterol level affects surface charge of lipid membranes in saline solution

Cholesterol is an important component of all biological membranes as well as drug delivery liposomes. We show here that increasing the level of cholesterol in a phospholipid membrane decreases surface charge in the physiological environment. Through molecular dynamics simulation we have shown that i...

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Detalles Bibliográficos
Autores principales: Magarkar, Aniket, Dhawan, Vivek, Kallinteri, Paraskevi, Viitala, Tapani, Elmowafy, Mohammed, Róg, Tomasz, Bunker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028897/
https://www.ncbi.nlm.nih.gov/pubmed/24845659
http://dx.doi.org/10.1038/srep05005