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Helicobacter pylori downregulates expression of human β-defensin 1 in the gastric mucosa in a type IV secretion-dependent fashion

Helicobacter pylori establishes a chronic lifelong infection in the human gastric mucosa, which may lead to peptic ulcer disease or gastric adenocarcinoma. The human beta-defensins (hβDs) are antimicrobial peptides, hβD1 being constitutively expressed in the human stomach. We hypothesized that H. py...

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Detalles Bibliográficos
Autores principales:	Patel, SR, Smith, K, Letley, DP, Cook, KW, Memon, AA, Ingram, RJM, Staples, E, Backert, S, Zaitoun, AM, Atherton, JC, Robinson, K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028989/ https://www.ncbi.nlm.nih.gov/pubmed/23870035 http://dx.doi.org/10.1111/cmi.12174

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