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Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report

Background and Purpose: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease clinically characterized by prominent axial extrapyramidal motor symptoms with frequent falls. Over the last years the introduction of robotic technologies to recover lower limb function has been greatly...

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Autores principales: Sale, Patrizio, Stocchi, Fabrizio, Galafate, Daniele, De Pandis, Maria Francesca, Le Pera, Domenica, Sova, Ivan, Galli, Manuela, Foti, Calogero, Franceschini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029018/
https://www.ncbi.nlm.nih.gov/pubmed/24860459
http://dx.doi.org/10.3389/fnhum.2014.00207
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author Sale, Patrizio
Stocchi, Fabrizio
Galafate, Daniele
De Pandis, Maria Francesca
Le Pera, Domenica
Sova, Ivan
Galli, Manuela
Foti, Calogero
Franceschini, Marco
author_facet Sale, Patrizio
Stocchi, Fabrizio
Galafate, Daniele
De Pandis, Maria Francesca
Le Pera, Domenica
Sova, Ivan
Galli, Manuela
Foti, Calogero
Franceschini, Marco
author_sort Sale, Patrizio
collection PubMed
description Background and Purpose: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease clinically characterized by prominent axial extrapyramidal motor symptoms with frequent falls. Over the last years the introduction of robotic technologies to recover lower limb function has been greatly employed in the rehabilitative practice. This observational trial is aimed at investigating the changes in the main spatiotemporal following end-effector robot training in people with PSP. Method: Pilot observational trial. Participants: Five cognitively intact participants with PSP and gait disorders. Interventions: Patients were submitted to a rehabilitative program of robot-assisted walking sessions for 45 min, 5 times a week for 4 weeks. Main outcome measures: The spatiotemporal parameters at the beginning (T0) and at the end of treatment (T1) were recorded by a gait analysis laboratory. Results: Robot training was feasible, acceptable and safe and all participants completed the prescribed training sessions. All patients showed an improvement in the gait spatiotemporal index (Mean velocity, Cadence, Step length, and Step width) (T0 vs. T1). Conclusions: Robot training is a feasible and safe form of rehabilitation for cognitively intact people with PSP. The lack of side effects and the positive results in the gait parameter index in all patients support the recommendation to extend the trials of this treatment. Further investigation regarding the effectiveness of robot training in time is necessary. Trial registration: ClinicalTrials.gov NCT01668407.
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spelling pubmed-40290182014-05-23 Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report Sale, Patrizio Stocchi, Fabrizio Galafate, Daniele De Pandis, Maria Francesca Le Pera, Domenica Sova, Ivan Galli, Manuela Foti, Calogero Franceschini, Marco Front Hum Neurosci Neuroscience Background and Purpose: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease clinically characterized by prominent axial extrapyramidal motor symptoms with frequent falls. Over the last years the introduction of robotic technologies to recover lower limb function has been greatly employed in the rehabilitative practice. This observational trial is aimed at investigating the changes in the main spatiotemporal following end-effector robot training in people with PSP. Method: Pilot observational trial. Participants: Five cognitively intact participants with PSP and gait disorders. Interventions: Patients were submitted to a rehabilitative program of robot-assisted walking sessions for 45 min, 5 times a week for 4 weeks. Main outcome measures: The spatiotemporal parameters at the beginning (T0) and at the end of treatment (T1) were recorded by a gait analysis laboratory. Results: Robot training was feasible, acceptable and safe and all participants completed the prescribed training sessions. All patients showed an improvement in the gait spatiotemporal index (Mean velocity, Cadence, Step length, and Step width) (T0 vs. T1). Conclusions: Robot training is a feasible and safe form of rehabilitation for cognitively intact people with PSP. The lack of side effects and the positive results in the gait parameter index in all patients support the recommendation to extend the trials of this treatment. Further investigation regarding the effectiveness of robot training in time is necessary. Trial registration: ClinicalTrials.gov NCT01668407. Frontiers Media S.A. 2014-04-17 /pmc/articles/PMC4029018/ /pubmed/24860459 http://dx.doi.org/10.3389/fnhum.2014.00207 Text en Copyright © 2014 Sale, Stocchi, Galafate, De Pandis, Le Pera, Sova, Galli, Foti and Franceschini. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Sale, Patrizio
Stocchi, Fabrizio
Galafate, Daniele
De Pandis, Maria Francesca
Le Pera, Domenica
Sova, Ivan
Galli, Manuela
Foti, Calogero
Franceschini, Marco
Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report
title Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report
title_full Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report
title_fullStr Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report
title_full_unstemmed Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report
title_short Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report
title_sort effects of robot assisted gait training in progressive supranuclear palsy (psp): a preliminary report
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029018/
https://www.ncbi.nlm.nih.gov/pubmed/24860459
http://dx.doi.org/10.3389/fnhum.2014.00207
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