Genetic dissection of the polyoxin building block-carbamoylpolyoxamic acid biosynthesis revealing the “pathway redundancy” in metabolic networks

BACKGROUND: Polyoxin, a peptidyl nucleoside antibiotic, consists of three building blocks including a nucleoside skeleton, polyoximic acid (POIA), and carbamoylpolyoxamic acid (CPOAA), however, little is known about the “pathway redundancy” of the metabolic networks directing the CPOAA biosynthesis...

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Detalles Bibliográficos
Autores principales: Chen, Wenqing, Dai, Daofeng, Wang, Changchun, Huang, Tingting, Zhai, Lipeng, Deng, Zixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029187/
https://www.ncbi.nlm.nih.gov/pubmed/24314013
http://dx.doi.org/10.1186/1475-2859-12-121

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