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5-Chloro-5′′-[4-(di­methyl­amino)­benzyl­idene]-4′-[4-(di­methyl­amino)­phen­yl]-1′,1′′-di­methyl­dispiro­[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

The title compound, C(34)H(38)ClN(5)O(2), has spiro links connecting the pyrrolidine ring and indole residue, as well as the piperidine and pyrrolidine rings. A half-chair conformation is found for the piperidine ring with the C atom connected to the spiro-C atom lying 0.738 (4) Å out of the plane o...

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Detalles Bibliográficos
Autores principales: Farag, I. S. Ahmed, Girgis, Adel S., Ramadan, A. A., Moustafa, A. M., Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029217/
https://www.ncbi.nlm.nih.gov/pubmed/24855471
http://dx.doi.org/10.1107/S1600536813033771
Descripción
Sumario:The title compound, C(34)H(38)ClN(5)O(2), has spiro links connecting the pyrrolidine ring and indole residue, as well as the piperidine and pyrrolidine rings. A half-chair conformation is found for the piperidine ring with the C atom connected to the spiro-C atom lying 0.738 (4) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.0407 Å). The methyl­ene C atom is the flap in the envelope conformation for the pyrrolidine ring. In the crystal, supra­molecular chains are sustained by alternating eight-membered {⋯HNCO}(2) and 14-membered {⋯HC(5)O}(2) synthons. Chains are connected into a three-dimensional network by (pyrrolidine-bound phenyl-meth­yl)C—H⋯π(pyrrolidine-bound phen­yl) edge-to-face inter­actions.