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5-Chloro-5′′-[4-(dimethylamino)benzylidene]-4′-[4-(dimethylamino)phenyl]-1′,1′′-dimethyldispiro[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione
The title compound, C(34)H(38)ClN(5)O(2), has spiro links connecting the pyrrolidine ring and indole residue, as well as the piperidine and pyrrolidine rings. A half-chair conformation is found for the piperidine ring with the C atom connected to the spiro-C atom lying 0.738 (4) Å out of the plane o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029217/ https://www.ncbi.nlm.nih.gov/pubmed/24855471 http://dx.doi.org/10.1107/S1600536813033771 |
Sumario: | The title compound, C(34)H(38)ClN(5)O(2), has spiro links connecting the pyrrolidine ring and indole residue, as well as the piperidine and pyrrolidine rings. A half-chair conformation is found for the piperidine ring with the C atom connected to the spiro-C atom lying 0.738 (4) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.0407 Å). The methylene C atom is the flap in the envelope conformation for the pyrrolidine ring. In the crystal, supramolecular chains are sustained by alternating eight-membered {⋯HNCO}(2) and 14-membered {⋯HC(5)O}(2) synthons. Chains are connected into a three-dimensional network by (pyrrolidine-bound phenyl-methyl)C—H⋯π(pyrrolidine-bound phenyl) edge-to-face interactions. |
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