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α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets
INTRODUCTION: Natalizumab blocks α4-integrins and is a prototypic agent for a series of anti-inflammatory drugs that impair trafficking of immune cells into the CNS. However, modulation of the access of immune cells to the CNS is associated with impaired immune surveillance and detrimental viral inf...
Autores principales: | Rothhammer, Veit, Muschaweckh, Andreas, Gasteiger, Georg, Petermann, Franziska, Heink, Sylvia, Busch, Dirk H, Heikenwälder, Mathias, Hemmer, Bernhard, Drexler, Ingo, Korn, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029267/ https://www.ncbi.nlm.nih.gov/pubmed/24606807 http://dx.doi.org/10.1186/2051-5960-2-27 |
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