Childhood cancers: what is a possible role of infectious agents?

The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include h...

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Autores principales: Alibek, Kenneth, Mussabekova, Assel, Kakpenova, Ainur, Duisembekova, Assem, Baiken, Yeldar, Aituov, Bauyrzhan, Karatayeva, Nargis, Zhussupbekova, Samal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029297/
https://www.ncbi.nlm.nih.gov/pubmed/24321500
http://dx.doi.org/10.1186/1750-9378-8-48
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author Alibek, Kenneth
Mussabekova, Assel
Kakpenova, Ainur
Duisembekova, Assem
Baiken, Yeldar
Aituov, Bauyrzhan
Karatayeva, Nargis
Zhussupbekova, Samal
author_facet Alibek, Kenneth
Mussabekova, Assel
Kakpenova, Ainur
Duisembekova, Assem
Baiken, Yeldar
Aituov, Bauyrzhan
Karatayeva, Nargis
Zhussupbekova, Samal
author_sort Alibek, Kenneth
collection PubMed
description The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.
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spelling pubmed-40292972014-05-22 Childhood cancers: what is a possible role of infectious agents? Alibek, Kenneth Mussabekova, Assel Kakpenova, Ainur Duisembekova, Assem Baiken, Yeldar Aituov, Bauyrzhan Karatayeva, Nargis Zhussupbekova, Samal Infect Agent Cancer Review The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed. BioMed Central 2013-12-10 /pmc/articles/PMC4029297/ /pubmed/24321500 http://dx.doi.org/10.1186/1750-9378-8-48 Text en Copyright © 2013 Alibek et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Alibek, Kenneth
Mussabekova, Assel
Kakpenova, Ainur
Duisembekova, Assem
Baiken, Yeldar
Aituov, Bauyrzhan
Karatayeva, Nargis
Zhussupbekova, Samal
Childhood cancers: what is a possible role of infectious agents?
title Childhood cancers: what is a possible role of infectious agents?
title_full Childhood cancers: what is a possible role of infectious agents?
title_fullStr Childhood cancers: what is a possible role of infectious agents?
title_full_unstemmed Childhood cancers: what is a possible role of infectious agents?
title_short Childhood cancers: what is a possible role of infectious agents?
title_sort childhood cancers: what is a possible role of infectious agents?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029297/
https://www.ncbi.nlm.nih.gov/pubmed/24321500
http://dx.doi.org/10.1186/1750-9378-8-48
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