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Reproducibility and reliability of SNP analysis using human cellular DNA at or near nanogram levels

BACKGROUND: Illumina SNP arrays have been routinely used for genome-wide association studies to identify potential biomarkers for various diseases. The recommended 200 ng of DNA for high-quality results is a roadblock to utilizing this assay when such quantities of DNA are not available. The goal of...

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Detalles Bibliográficos
Autores principales: Okitsu, Cindy Y, Van Den Berg, David J, Lieber, Michael R, Hsieh, Chih-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029319/
https://www.ncbi.nlm.nih.gov/pubmed/24314330
http://dx.doi.org/10.1186/1756-0500-6-515

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