Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer

BACKGROUND: Oncogenic mechanisms in small-cell lung cancer remain poorly understood leaving this tumor with the worst prognosis among all lung cancers. Unlike other cancer types, sequencing genomic approaches have been of limited success in small-cell lung cancer, i.e., no mutated oncogenes with pot...

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Detalles Bibliográficos
Autores principales: Udyavar, Akshata R, Hoeksema, Megan D, Clark, Jonathan E, Zou, Yong, Tang, Zuojian, Li, Zhiguo, Li, Ming, Chen, Heidi, Statnikov, Alexander, Shyr, Yu, Liebler, Daniel C, Field, John, Eisenberg, Rosana, Estrada, Lourdes, Massion, Pierre P, Quaranta, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029366/
https://www.ncbi.nlm.nih.gov/pubmed/24564859
http://dx.doi.org/10.1186/1752-0509-7-S5-S1

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