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Active enhancer positions can be accurately predicted from chromatin marks and collective sequence motif data

BACKGROUND: Transcriptional regulation in multi-cellular organisms is a complex process involving multiple modular regulatory elements for each gene. Building whole-genome models of transcriptional networks requires mapping all relevant enhancers and then linking them to target genes. Previous metho...

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Detalles Bibliográficos
Autores principales: Podsiadło, Agnieszka, Wrzesień, Mariusz, Paja, Wiesław, Rudnicki, Witold, Wilczyński, Bartek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029456/
https://www.ncbi.nlm.nih.gov/pubmed/24565409
http://dx.doi.org/10.1186/1752-0509-7-S6-S16